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John McLean

Dr, Programme Leader

19992011
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Personal profile

Overview

I worked in industry before joining UWS. I have experience in the fields of drug discovery and disease models. At present, I am Programme Leader for the biomedical science programmes at both undergraduate and postgraduate level.

Research Interests:

Gene expression in disease

Recombinant gene expression in mammalian cells

https://scholar.google.co.uk/citations?user=DetVpCcAAAAJ&hl=en

Fingerprint Dive into the research topics where John McLean is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
PAR-2 Receptor Medicine & Life Sciences
Joints Medicine & Life Sciences
Indomethacin Medicine & Life Sciences
Cyclooxygenase 1 Medicine & Life Sciences
Prostaglandins Medicine & Life Sciences
Knee Medicine & Life Sciences
Cyclooxygenase 2 Medicine & Life Sciences
Prostaglandin-Endoperoxide Synthases Medicine & Life Sciences

Research Output 1999 2011

  • 8 Article
  • 1 Conference contribution
  • 1 Poster

Work-based learning in the biosciences

Tatner, P., Tedford, C., Bulloch, J., McLean, J. & Hettle, S., 2011.

Research output: Contribution to conferencePoster

Open Access
File

Therapeutic promise of proteinase-activated receptor-2 antagonism in joint inflammation

Kelso, E. B., Lockhart, J. C., Hembrough, T., Dunning, L., Plevin, R., Hollenberg, M. D., Sommerhoff, C. P., McLean, J. S. & Ferrell, W. R., 2006, In : Journal of Pharmacology and Experimental Therapeutics. 316, 3, p. 1017-1024 8 p.

Research output: Contribution to journalArticle

PAR-2 Receptor
Joints
Inflammation
Kaolin
Carrageenan

Combined inhibition of nitrergic and prostanoid pathways in J774 macrophages

Day, S. M., McLean, J. S., Lockhart, J. C. & Ferrell, W. R., 2003, In : Clinical Experimental Rheumatology. 21, p. 625-631 7 p.

Research output: Contribution to journalArticle

NG-Nitroarginine Methyl Ester
Prostaglandins
Macrophages
Dinoprostone
Indomethacin

Essential role for proteinase activated receptor-2 in arthritis

Ferrell, W. R., Lockhart, J. C., Kelso, E. B., Dunning, L., Plevin, R., Meek, S. E., Smith, A. J. H., Hunter, G. D., McLean, J. S., McGarry, F., Ramage, R., Jiang, L., Kanke, T. & Kawagoe, J., 2003, In : The Journal of Clinical Investigation. 111, p. 35-41 7 p.

Research output: Contribution to journalArticle

Open Access
PAR-2 Receptor
Arthritis
Inflammation
Joints
Intra-Articular Injections

Pathophysiological basis of acute inflammatory hyperaemia in the rat knee: roles of cyclooxygenase- 1 and -2.

Egan, C. G., McLean, J. S., Ferrell, W. R., Day, S. M. & Mclean, J. S., 2002, In : Journal of Physiology. p. 579-587 9 p.

Research output: Contribution to journalArticle

Cyclooxygenase 1
Hyperemia
Cyclooxygenase 2
Indomethacin
Knee

Profiles