19972019
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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Erythrocyte Membrane Medicine & Life Sciences
Oxidative Stress Medicine & Life Sciences
Exercise Medicine & Life Sciences
Erythrocytes Medicine & Life Sciences
Chlorpromazine Medicine & Life Sciences
Hepatocytes Medicine & Life Sciences
Chronic Kidney Failure Medicine & Life Sciences
Stem Cells Medicine & Life Sciences

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Research Output 1997 2019

Chlorpromazine toxicity is associated with disruption of cell membrane integrity and initiation of a pro-inflammatory response in the HepaRG hepatic cell line

Morgan, K., Martucci, N., Kozlowska, A., Gamal, W., Brzeszczynki, F., Treskes, P., Samuel, K., Hayes, P., Nelson, L., Bagnaninchi, P., Brzeszczynska, J. & Plevris, J., 19 Jan 2019, In : Biomedicine & Pharmacotherapy. 111, p. 1408-1416 9 p.

Research output: Contribution to journalArticle

Open Access
Chlorpromazine
Hepatocytes
Cell Membrane
Cell Line
Poisons

Double-headed small bowel capsule endoscopy: real-world experience at a tertiary referral centre

Yung, D. E., Douglas, S., Brzeszczynska, J., Plevris, J. N. & Koulaouzidis, A., 18 Mar 2019, In : Endoscopy. 51, 04, S9.

Research output: Contribution to journalMeeting Abstract

Capsule Endoscopy
Tertiary Care Centers
Head
Pathology
Inflammatory Bowel Diseases

Towards understanding the mechanisms of chlorpromazine-induced hepatic toxicity using a human HepaRG-based model

Brzeszczynska, J., Morgan, K., Brzeszczynski, F., Samuel, K., Hayes, P. & Plevris, J., 23 Apr 2018, In : Journal of Hepatology. 68, Supplement 1, p. S141-S141 1 p., THU-040.

Research output: Contribution to journalMeeting Abstract

Chlorpromazine
Liver
Tight Junctions
Bile Acids and Salts
Oxidative Stress

Alterations in the in vitro and in vivo regulation of muscle regeneration in healthy ageing and the influence of sarcopenia

Brzeszczyńska, J., Meyer, A., McGregor, R., Schilb, A., Degen, S., Tadini, V., Johns, N., Langen, R., Schols, A., Glass, D. J., Roubenoff, R., Ross, J. A., Fearon, K. C. H., Greig, C. A. & Jacobi, C., 6 Dec 2017, In : Journal of Cachexia, Sarcopenia and Muscle. 9, 1, p. 93-105 13 p.

Research output: Contribution to journalArticle

Open Access
Sarcopenia
Muscle Development
Regeneration
Muscles
Up-Regulation

Hepatic differentiation of human iPSCs in different 3D models: a comparative study

Meier, F., Freyer, N., Brzeszczynska, J., Knöspel, F., Armstrong, L., Lako, M., Greuel, S., Damm, G., Ludwig-Schwellinger, E., Deschl, U., Ross, J. A., Beilmann, M. & Zeilinger, K., 16 Oct 2017, In : International Journal of Molecular Medicine. 40, 6, p. 1759-1771 13 p.

Research output: Contribution to journalArticle

Open Access
Induced Pluripotent Stem Cells
Bioreactors
Liver
Hepatocytes
Hepatocyte Nuclear Factor 4

Activities 2019 2019

BREATH team meeting with Clinical & Biomedical Team at Dumfries & Gallloway Royal Infirmary

John Lockhart (Organiser), Gary Litherland (Organiser), Joanna Brzeszczynska (Participant), Carly Woods (Participant), Phyllis Murphie (Participant), Adele Foster (Participant)
13 Mar 2019

Activity: Other

BREATH team meeting with Clinical team at Ayr Hospital

John Lockhart (Participant), Gary Litherland (Organiser), Joanna Brzeszczynska (Participant), Karen Bell (Participant), Anur Guhan (Participant)
28 Feb 2019

Activity: Other

Meeting with Glasgow Respiratory Clinicians

John Lockhart (Participant), Andrew MacKenzie (Organiser), Gary Litherland (Participant), Anne Crilly (Participant), William MacKay (Participant), Craig Williams (Participant), Joanna Brzeszczynska (Participant), Mariarca Bailo (Presenter), Kirsty McCallum (Presenter), Bryn Short (Presenter), Kimberly Black (Presenter), Fawziye Tarhini (Presenter), David Anderson (Participant), Hannah Bayes (Participant), Pallavai Bedi (Participant)
8 Feb 2019

Activity: Other