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Research Output

  • 15 Article
  • 1 Commissioned report
  • 1 Comment/debate
2018

Exposure to an anti-androgenic herbicide negatively impacts reproductive physiology and fertility in Xenopus tropicalis

Orton, F., Safholm, M., Jansson, E., Carlsson, Y., Fick, J., Uren Webster, T., McMillan, T., Leishman, M., Verbruggen, B., Economou, T., Tyler, C. R. & Berg, C., 14 Jun 2018, In : Scientific Reports. 2018, 8, 15 p., 9124.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
130 Downloads (Pure)
2016

Effects of Common Pesticides on Prostaglandin D2 (PGD2) Inhibition in SC5 Mouse Sertoli Cells, Evidence of Binding at the COX-2 Active Site, and Implications for Endocrine Disruption

Kugathas, S., Audouze, K., Ermler, S., Orton, F., Rosivatz, E., Scholze, M. & Kortenkamp, A., Apr 2016, In : Environmental Health Perspectives. 124, 4, p. 452-459

Research output: Contribution to journalArticle

Open Access
13 Citations (Scopus)
2015

A novel biomarker for anti-androgenic activity in placenta reveals risks of urogenital malformations

Arrebola, J. P., Molina-Molina, J. M., Fernandez, M. F., Saenz, J. M., Amaya, E., Indiveri, P., Hill, E. M., Scholze, M., Orton, F., Kortenkamp, A. & Olea, N., Jun 2015, In : Reproduction. 149, 6, p. 605-613

Research output: Contribution to journalArticle

7 Citations (Scopus)

Do hormone-modulating chemicals impact on reproduction and development of wild amphibians?

Orton, F. & Tyler, C. R., Nov 2015, In : Biological Reviews. 90, 4, p. 1100-1117

Research output: Contribution to journalArticle

45 Citations (Scopus)

Screening breeding sites of the common toad (Bufo bufo) in England and Wales for evidence of endocrine disrupting activity (vol 117, pg 7, 2015)

Pickford, D. B., Jones, A., Velez-Pelez, A., Orton, F., Iguchi, T., Mitsui, N. & Tooi, O., Oct 2015, In : Ecotoxicology and Environmental Safety. 120, p. 473-473

Research output: Contribution to journalArticle

2014

Body size, nuptial pad size and hormone levels: potential non-destructive biomarkers of reproductive health in wild toads (Bufo bufo)

Orton, F., Baynes, A., Clare, F., Duffus, A. L. J., Larroze, S., Scholze, M. & Garner, T. W. J., Sep 2014, In : Ecotoxicology. 23, 7, p. 1359-1365

Research output: Contribution to journalArticle

13 Citations (Scopus)

Mixture effects at very low doses with combinations of anti-androgenic pesticides, antioxidants, industrial pollutant and chemicals used in personal care products

Orton, F., Ermler, S., Kugathas, S., Rosivatz, E., Scholze, M. & Kortenkamp, A., 1 Aug 2014, In : Toxicology and Applied Pharmacology. 278, 3, p. 201-208

Research output: Contribution to journalArticle

Open Access
62 Citations (Scopus)
2013

Batrachochytrium dendrobatidis Infection and Lethal Chytridiomycosis in Caecilian Amphibians (Gymnophiona)

Gower, D. J., Doherty-Bone, T., Loader, S. P., Wilkinson, M., Kouete, M. T., Tapley, B., Orton, F., Daniel, O. Z., Wynne, F., Flach, E., Mueller, H., Menegon, M., Stephen, I., Browne, R. K., Fisher, M. C., Cunningham, A. A. & Garner, T. W. J., Jun 2013, In : EcoHealth. 10, 2, p. 173-183

Research output: Contribution to journalArticle

40 Citations (Scopus)
2012

Competitive Androgen Receptor Antagonism as a Factor Determining the Predictability of Cumulative Antiandrogenic Effects of Widely Used Pesticides

Orton, F., Rosivatz, E., Scholze, M. & Kortenkamp, A., Nov 2012, In : Environmental Health Perspectives. 120, 11, p. 1578-1584

Research output: Contribution to journalArticle

Open Access
25 Citations (Scopus)

Response to A critique of the European Commission Document, "State of the Art Assessment of Endocrine Disrupters" by Rhomberg and colleagues - letter to the editor

Kortenkamp, A., Martin, O., Evans, R., Orton, F., McKinlay, R., Rosivatz, E. & Faust, M., Oct 2012, In : Critical Reviews in Toxicology. 42, 9, p. 787-789

Research output: Contribution to journalComment/debate

13 Citations (Scopus)
2011

Agricultural intensity in ovo affects growth, metamorphic development and sexual differentiation in the Common toad (Bufo bufo)

Orton, F. & Routledge, E., Jun 2011, In : Ecotoxicology. 20, 4, p. 901-911

Research output: Contribution to journalArticle

20 Citations (Scopus)

Demasculinization and feminization of male gonads by atrazine: Consistent effects across vertebrate classes

Hayes, T. B., Anderson, L. L., Beasley, V. R., de Solla, S. R., Iguchi, T., Ingraham, H., Kestemont, P., Kniewald, J., Kniewald, Z., Langlois, V. S., Luque, E. H., McCoy, K. A., Munoz-de-Toro, M., Oka, T., Oliveira, C. A., Orton, F., Ruby, S., Suzawa, M., Tavera-Mendoza, L. E., Trudeau, V. L. & 2 others, Victor-Costa, A. B. & Willingham, E., Oct 2011, In : Journal of Steroid Biochemistry and Molecular Biology. 127, 1-2, p. 64-73

Research output: Contribution to journalArticle

180 Citations (Scopus)

State of the art assessment of endocrine disruptors: Final Report

Kortenkamp, A., Martin, O., Faust, M., Evans, R., McKinlay, R., Orton, F. & Rosivatz, E., Dec 2011, European Commission. 135 p.

Research output: Book/ReportCommissioned report

Widely Used Pesticides with Previously Unknown Endocrine Activity Revealed as in Vitro Antiandrogens

Orton, F., Rosivatz, E., Scholze, M. & Kortenkamp, A., Jun 2011, In : Environmental Health Perspectives. 119, 6, p. 794-800

Research output: Contribution to journalArticle

Open Access
98 Citations (Scopus)
2009

Endocrine Disrupting Effects of Herbicides and Pentachlorophenol: In Vitro and in Vivo Evidence

Orton, F., Lutz, I., Kloas, W. & Routledge, E. J., 15 Mar 2009, In : Environmental Science and Technology. 43, 6, p. 2144-2150

Research output: Contribution to journalArticle

112 Citations (Scopus)

Remarkable amphibian diversity in the South Nguru Mountains, Tanzania

Loader, S. P., Menegon, M., Müller, H., Gower, D. J., Wilkinson, M., Howell, K. M. & Orton, F., 2009, Froglog, 91, p. 8-10.

Research output: Contribution to specialist publicationArticle

Open Access
2006

Effects of nitrate and atrazine on larval development and sexual differentiation in the northern leopard frog Rana pipiens

Orton, F., Carr, J. A. & Handy, R. D., Jan 2006, In : Environmental Toxicology and Chemistry. 25, 1, p. 65-71 7 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)