Research Output per year
Area of academic expertise - outline
My research career began with my doctoral studies at the University of Strathclyde investigating the ability of the female sex hormone progesterone to modulate immune cell function. During this time I was introduced to the parasite Toxoplasma gondii and gained interest in how this parasite is controlled by the immune system and how it can be congenitally transmitted from mother to baby.
As a post-doctoral researcher within Reproductive & Maternal Medicine at the University of Glasgow, I was able to continue my studies into various aspects of reproductive immunology, including investigations into the trafficking of leukocytes to the uterus, and the role of the atypical chemokine receptor ACKR2 within the placenta.
Since joining UWS in 2013, my primary area of research interest is Reproductive Immunology, with a specific focus on human pregnancy.
I am also passionate about science communication and public engagement. I am a registered STEM ambassador, have vast experience of different engagement activities, and play a key role within the School of Science & Sport in the coordination and reporting of external engagement activities.
Current research activities
Current projects include: (a) characterisation of the expression of chemokines in the non-pregnant uterus; (b) an investigation into the role of IL-33 in the placenta; (c) an investigation into the role of ACKR2 in the placenta; and (d) studies into the control of infection-induced inflammation in the placenta, focussing on using Toxoplasma gondii as our model infection.
Desired research direction
It is my ambition to expand and develop Reproductive Immunology projects at UWS so that we are recognised internationally as a key institution for research in this area. Current and planned projects will be developed to become translational to the clinic and have wider impact on clinical practice, health education and policy.
Target collaborative companies
- Biotechnology Industry - Interested in working with companies seeking help with developing better diagnostic assays/tools for inflammatory conditions.
- Continuing Professional Development – Interested in working with any training provider to develop science communication and skills update programmes.
Target collaborative organisations
- NHS (Greater Glasgow & Clyde & Lanarkshire)
- Renfrewshire/South Lanarkshire Council
- Collaborations with Universities of Glasgow & Strathclyde are ongoing, but I am also keen to work with any institution to develop new collaborations.
Research output: Contribution to journal › Review article
Research output: Chapter in Book/Report/Conference proceeding › Chapter
Atypical chemokine receptor ACKR2 mediates chemokine scavenging by primary human trophoblasts and can regulate fetal growth, placental structure, and neonatal mortality in miceTeoh, P. J., Menzies, F. M., Hansell, C. A. H., Clarke, M., Waddell, C., Burton, G. J., Nelson, S. M. & Nibbs, R. J. B. 15 Nov 2014 In : The Journal of Immunology. 193, 10, p. 5218-5228 11 p.
Research output: Contribution to journal › Article
Investigating the expression of matrix metalloproteinases and heat shock proteins in postpartum uterine involutionBurton, L. E., Oldham, R. S., Higgins, C. A., Nibbs, R. J. B., Nelson, S. M. & Menzies, F. M. 2 Sep 2014 In : Scottish Medical Journal. 59, 3, p. E34-E34 1 p.
Research output: Contribution to journal › Meeting Abstract
The atypical chemokine receptor D6 is expressed by trophoblasts and plays roles in placental formation and chemokine scavengingMenzies, F., Teoh, P. J., Waddell, C., Nelson, S. M. & Nibbs, R. J. B. Aug 2013
Research output: Contribution to conference › Abstract
Activities per year
Activity: Types of Public engagement and outreach - Festival/Exhibition