Personal profile
Area of academic expertise - outline
I have an extensive background in the creation of functional nanomaterials. This work was focussed on the development of biological nanoprobes coupled with advanced spectroscopies for the detection of diseases. This encompassed the synthesis of a variety of nanoparticles, their functionalisation with a range of biological probe molecules such as DNA, antibodies and proteins and their use in sensitive assay systems. To drive this work forward I developed skills in chemical synthesis, the handling and use of delicate biological materials and coupling methods to attach these molecule to nanoparticle. To characterise the nanoprobes I used UV-Visible spectrometry, High Performance Liquid Chromatography, Scanning Electron Microscopy, Fluorescence Microscopy, Dynamic Light Scattering and Zeta Potential instruments, to name a few. For the assay detection I used Surface enhanced Raman Scattering.
Current research activities
My current research efforts are focussed on the creation of nanocomposites that combine the optimal attributes of metallic nanoparticles with the biological compatibilty and drug retention characteristics of polymers. The aim is the creation of a targeted treatment for diseases such as cancer.
I am also interested in the development of new methods for the analysis of nanoparticle pollution in the environment.
Desired research direction
The overall aim of my research is the use of nanoscience to improve human health and well being through the development of new detection and treatment methods for diseases.
Other areas of expertise available for knowledge exchange
I have a background in analytical chemistry with a focus on forensic science so have expertise in drug detection and poison analysis.
Target collaborative companies
I would be interested in working with companies looking to harness nanoscience and nanoparticles to provide innovative solutions for issues involving improving human health and enhancing sustainability.
Target collaborative organisations
With my background in nanoscience I would be very interesting in collaborating with like minded individuals to produce novel therapeutic and diagnostic agents.
External positions
Reviewer for RSC Advances, Royal Society of Chemistry
1 Oct 2019 → …
Keywords
- QD Chemistry
- Nanoscience
- Bionanotechnology
- Nanocomposites
- DNA
- Nanoparticles
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Corrosive substance attacks: linking the weapon to the damage
Thompson, D., 20 Jun 2022.Research output: Contribution to conference › Presentation › peer-review
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From synthetic DNA to PCR product: detection of fungal infections using SERS
Mabbott, S., Thompson, D., Sirimuthu, N., McNay, G., Faulds, K. & Graham, D., 1 Jun 2016, In: Faraday Discussions. 187, p. 461-472 11 p.Research output: Contribution to journal › Article › peer-review
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Palladium(0) NHC complexes: a new avenue to highly efficient phosphorescence
Henwood, A. F., Lesieur, M., Bansal, A. K., Lemaur, V., Beljonne, D., Thompson, D. G., Graham, D., Slawin, A. M. Z., Samuel, I. D. W., Cazin, C. S. J. & Zysman-Colman, E., 2 Apr 2015, In: Chemical Science. 6, 5, p. 3248-3261 14 p.Research output: Contribution to journal › Article › peer-review
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SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy
Kashmery, H. A., Thompson, D. G., Dondi, R., Mabbott, S., Graham, D., Clark, A. W. & Burley, G. A., 2015, In: ChemComm. 51, 65, p. 13028-13031 4 p.Research output: Contribution to journal › Article › peer-review
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Engineering DNA binding sites to assemble and tune plasmonic nanostructures
Clark, A. W., Thompson, D. G., Graham, D. & Cooper, J. M., 2 Jul 2014, In: Advanced Materials. 26, 25, p. 4286-4292 7 p.Research output: Contribution to journal › Article › peer-review
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Creation of Nanocomposites for Enhanced Bioanalysis
Thompson, D. (Speaker)
27 Jun 2018Activity: Talk or presentation › Oral presentation
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Creation of Nanocomposites for Enhanced Bioanalysis
Thompson, D. (Speaker)
6 Jun 2018Activity: Talk or presentation › Oral presentation
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Nanoscience for Improving Health
Thompson, D. (Speaker)
25 May 2018Activity: Talk or presentation › Oral presentation
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Learning Innovation (Organisational unit)
Thompson, D. (Member)
Nov 2016 → …Activity: Membership › Membership of network
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School of Health and Life Sciences (Organisational unit)
Thompson, D. (Chair)
Sept 2016 → …Activity: Membership › Membership of network