20082016

Research output per year

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Personal profile

Area of academic expertise - outline

I have an extensive background in the creation of functional nanomaterials. This work was focussed on the development of biological nanoprobes coupled with advanced spectroscopies for the detection of diseases. This encompassed the synthesis of a variety of nanoparticles, their functionalisation with a range of biological probe molecules such as DNA, antibodies and proteins and their use in sensitive assay systems. To drive this work forward I developed skills in chemical synthesis, the handling and use of delicate biological materials and coupling methods to attach these molecule to nanoparticle. To characterise the nanoprobes I used UV-Visible spectrometry, High Performance Liquid Chromatography, Scanning Electron Microscopy, Fluorescence Microscopy, Dynamic Light Scattering and Zeta Potential instruments, to name a few. For the assay detection I used Surface enhanced Raman Scattering.

Current research activities

My current research efforts are focussed on the creation of nanocomposites that combine the optimal attributes of metallic nanoparticles with the biological compatibilty and drug retention characteristics of polymers. The aim is the creation of a targeted treatment for diseases such as cancer.

I am also interested in the development of new methods for the analysis of nanoparticle pollution in the environment.

Desired research direction

The overall aim of my research is the use of nanoscience to improve human health and well being through the development of new detection and treatment methods for diseases.

Other areas of expertise available for knowledge exchange

I have a background in analytical chemistry with a focus on forensic science so have expertise in drug detection and poison analysis.

Target collaborative companies

I would be interested in working with companies looking to harness nanoscience and nanoparticles to provide innovative solutions for issues involving improving human health and enhancing sustainability.

Target collaborative organisations

With my background in nanoscience I would be very interesting in collaborating with like minded individuals to produce novel therapeutic and diagnostic agents.

Keywords

  • QD Chemistry
  • Nanoscience
  • Bionanotechnology
  • Nanocomposites
  • DNA
  • Nanoparticles

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Research Output

From synthetic DNA to PCR product: detection of fungal infections using SERS

Mabbott, S., Thompson, D., Sirimuthu, N., McNay, G., Faulds, K. & Graham, D., 1 Jun 2016, In : Faraday Discussions. 187, p. 461-472 11 p.

Research output: Contribution to journalArticle

Open Access
  • 11 Citations (Scopus)

    Palladium(0) NHC complexes: a new avenue to highly efficient phosphorescence

    Henwood, A. F., Lesieur, M., Bansal, A. K., Lemaur, V., Beljonne, D., Thompson, D. G., Graham, D., Slawin, A. M. Z., Samuel, I. D. W., Cazin, C. S. J. & Zysman-Colman, E., 2 Apr 2015, In : Chemical Science. 6, 5, p. 3248-3261 14 p.

    Research output: Contribution to journalArticle

    Open Access
    21 Citations (Scopus)

    SERS enhancement of silver nanoparticles prepared by a template-directed triazole ligand strategy

    Kashmery, H. A., Thompson, D. G., Dondi, R., Mabbott, S., Graham, D., Clark, A. W. & Burley, G. A., 2015, In : ChemComm. 51, 65, p. 13028-13031 4 p.

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Engineering DNA binding sites to assemble and tune plasmonic nanostructures

    Clark, A. W., Thompson, D. G., Graham, D. & Cooper, J. M., 2 Jul 2014, In : Advanced Materials. 26, 25, p. 4286-4292 7 p.

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Synthesis, characterization and luminescence studies of gold(I)-NHC amide complexes

    Gómez-Suárez, A., Nelson, D. J., Thompson, D. G., Cordes, D. B., Graham, D., Slawin, A. M. Z. & Nolan, S. P., 28 Oct 2013, In : Beilstein Journal of Organic Chemistry. 9, p. 2216-2223 8 p.

    Research output: Contribution to journalArticle

    Open Access
    11 Citations (Scopus)

    Activities

    • 3 Oral presentation
    • 2 Membership of network
    • 1 Invited talk

    Nanoscience for Improving Health

    David Thompson (Speaker)

    25 May 2018

    Activity: Talk or presentationOral presentation

    Creation of Nanocomposites for Enhanced Bioanalysis

    David Thompson (Speaker)

    6 Jun 2018

    Activity: Talk or presentationOral presentation

    Creation of Nanocomposites for Enhanced Bioanalysis

    David Thompson (Speaker)

    27 Jun 2018

    Activity: Talk or presentationOral presentation

    School of Health and Life Sciences (Organisational unit)

    David Thompson (Chair)

    Sep 2016 → …

    Activity: MembershipMembership of network

    Learning Innovation (Organisational unit)

    David Thompson (Member)

    Nov 2016 → …

    Activity: MembershipMembership of network