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Personal profile

Area of academic expertise - outline

I have an extensive background in the creation of functional nanomaterials. This work was focussed on the development of biological nanoprobes coupled with advanced spectroscopies for the detection of diseases. This encompassed the synthesis of a variety of nanoparticles, their functionalisation with a range of biological probe molecules such as DNA, antibodies and proteins and their use in sensitive assay systems. To drive this work forward I developed skills in chemical synthesis, the handling and use of delicate biological materials and coupling methods to attach these molecule to nanoparticle. To characterise the nanoprobes I used UV-Visible spectrometry, High Performance Liquid Chromatography, Scanning Electron Microscopy, Fluorescence Microscopy, Dynamic Light Scattering and Zeta Potential instruments, to name a few. For the assay detection I used Surface enhanced Raman Scattering.

Current research activities

My current research efforts are focussed on the creation of nanocomposites that combine the optimal attributes of metallic nanoparticles with the biological compatibilty and drug retention characteristics of polymers. The aim is the creation of a targeted treatment for diseases such as cancer.

I am also interested in the development of new methods for the analysis of nanoparticle pollution in the environment.

Desired research direction

The overall aim of my research is the use of nanoscience to improve human health and well being through the development of new detection and treatment methods for diseases.

Other areas of expertise available for knowledge exchange

I have a background in analytical chemistry with a focus on forensic science so have expertise in drug detection and poison analysis.

Target collaborative companies

I would be interested in working with companies looking to harness nanoscience and nanoparticles to provide innovative solutions for issues involving improving human health and enhancing sustainability.

Target collaborative organisations

With my background in nanoscience I would be very interesting in collaborating with like minded individuals to produce novel therapeutic and diagnostic agents.

Keywords

  • QD Chemistry
  • Nanoscience
  • Bionanotechnology
  • Nanocomposites
  • DNA
  • Nanoparticles

Fingerprint Dive into the research topics where David Thompson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
Nanoparticles Chemical Compounds
Raman scattering Chemical Compounds
DNA Chemical Compounds
Raman Spectrum Analysis Medicine & Life Sciences
Oligonucleotides Engineering & Materials Science
Metal Nanoparticles Medicine & Life Sciences
Silver Chemical Compounds
Nucleic acid sequences Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2008 2016

From synthetic DNA to PCR product: detection of fungal infections using SERS

Mabbott, S., Thompson, D., Sirimuthu, N., McNay, G., Faulds, K. & Graham, D., 1 Jun 2016, In : Faraday Discussions. 187, p. 461-472 11 p.

Research output: Contribution to journalArticle

infectious diseases
Raman scattering
Candida
deoxyribonucleic acid
Raman spectra

Engineering DNA binding sites to assemble and tune plasmonic nanostructures

Clark, A. W., Thompson, D. G., Graham, D. & Cooper, J. M., 2 Jul 2014, In : Advanced Materials. 26, 25, p. 4286-4292 7 p.

Research output: Contribution to journalArticle

Synthesis, characterization and luminescence studies of gold(I)-NHC amide complexes

Gómez-Suárez, A., Nelson, D. J., Thompson, D. G., Cordes, D. B., Graham, D., Slawin, A. M. Z. & Nolan, S. P., 28 Oct 2013, In : Beilstein Journal of Organic Chemistry. 9, p. 2216-2223 8 p.

Research output: Contribution to journalArticle

Open Access

Combining functionalised nanoparticles and SERS for the detection of DNA relating to disease

Graham, D., Stevenson, R., Thompson, D. G., Barrett, L., Dalton, C. & Faulds, K., 2011, In : Faraday Discussions. 149, p. 291-299 9 p.

Research output: Contribution to journalArticle

Activities 2016 2018

  • 3 Oral presentation
  • 2 Membership of network
  • 1 Invited talk

Nanoscience for Improving Health

David Thompson (Speaker)
25 May 2018

Activity: Talk or presentationOral presentation

Creation of Nanocomposites for Enhanced Bioanalysis

David Thompson (Speaker)
6 Jun 2018

Activity: Talk or presentationOral presentation

Creation of Nanocomposites for Enhanced Bioanalysis

David Thompson (Speaker)
27 Jun 2018

Activity: Talk or presentationOral presentation

Learning Innovation (Organisational unit)

David Thompson (Member)
Nov 2016 → …

Activity: MembershipMembership of network

Coded Nanoparticles for DNA Detection

David Thompson (Speaker)
23 Mar 2016

Activity: Talk or presentationInvited talk